UNC 926 hydrochloride ( —— )

产品货号. M17174 CAS No. 1184136-10-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

UNC 926 hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

UNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3.
产品描述

UNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3. UNC-926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC-926 has not an effect on the binding of 53BP1 to H4K20me1.
同义词

——
通路

Others
靶点

Other Targets
受体

L3MBTL1
研究领域

Others-Field
适应症

——

1. Herold JM, et al. Structure–activity relationships of methyl-lysine reader antagonists. MedChemComm. 2012;3(45):45–51.

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